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公開データ一覧

公開対象　in vivoデータ in vitroデータへ
	化合物名（英）	溶媒	投与経路	臓器	単回試験投与量 （mg/kg）			反復試験投与量 （mg/kg）			備考
					Low	Middle	High	Low	Middle	High
1	acetaminophen	0.5% MC	Gavage	Liver / Kidney	300	600	1000	300	600	1000
2	isoniazid	0.5% MC	Gavage	Liver	200	600	2000	50	100	200
3	carbon tetrachloride	corn oil	Gavage	Liver	30	100	300	30	100	300
4	phenobarbital	0.5% MC	Gavage	Liver	100	150	300	10	30	100
5	valproic acid	0.5% MC	Gavage	Liver / Kidney	45	150	450	45	150	450
6	clofibrate	corn oil	Gavage	Liver / Kidney	30	100	300	30	100	300
7	rifampicin	0.5% MC	Gavage	Liver / Kidney	20	60	200	20	60	200
8	naphthyl isothiocyanate	corn oil	Gavage	Liver	15	50	150	1.5	5	15
9	allyl alcohol	corn oil	Gavage	Liver / Kidney	3	10	30	3	10	30
10	phenylbutazone	0.5% MC	Gavage	Liver / Kidney	20	60	200	20	60	200
11	omeprazole	0.5% MC	Gavage	Liver / Kidney	100	300	1000	100	300	1000
12	ethionine	0.5% MC	Gavage	Liver / Kidney	25	80	250	25	80	250
13	aspirin	0.5% MC	Gavage	Liver	450	1000	2000	45	150	450
14	indomethacin	0.5% MC	Gavage	Liver	5	15	50	0.5	1.6	5
				Kidney	0.5	1.6	5	0.5	1.6	5
15	chlorpromazine	0.5% MC	Gavage	Liver	45	150	NoData	4.5	15	45
16	thioacetamide	0.5% MC	Gavage	Liver / Kidney	4.5	15	45	4.5	15	45
17	carbamazepine	0.5% MC	Gavage	Liver	30	100	300	30	100	300
18	diclofenac	0.5% MC	Gavage	Liver	10	30	100	1	3	10
19	nitrofurantoin	0.5% MC	Gavage	Liver	100	300	600	10	30	100
				Kidney	10	30	100	10	30	100
20	benzbromarone	0.5% MC	Gavage	Liver	20	60	200	20	60	200
21	hexachlorobenzene	corn oil	Gavage	Liver / Kidney	300	1000	2000	30	100	300
22	diazepam	0.5% MC	Gavage	Liver	25	75	250	25	75	250
23	cyclophosphamide	0.5% MC	Gavage	Liver	15	50	150	1.5	5	15
				Kidney	1.5	5	15	1.5	5	15
24	methapyrilene	0.5% MC	Gavage	Liver	10	30	100	10	30	100
25	phenytoin	0.5% MC	Gavage	Liver	600	1200	2000	60	200	600
26	coumarin	corn oil	Gavage	Liver	15	50	150	15	50	150
27	allopurinol	0.5% MC	Gavage	Liver / Kidney	15	50	150	15	50	150
28	propylthiouracil	0.5% MC	Gavage	Liver	10	30	100	10	30	100
29	WY-14643	corn oil	Gavage	Liver	10	30	100	10	30	100
30	gemfibrozil	corn oil	Gavage	Liver	30	100	300	30	100	300
31	bromobenzene	corn oil	Gavage	Liver / Kidney	30	100	300	30	100	300
32	amiodarone	0.5% MC	Gavage	Liver	200	600	2000	20	60	200
33	sulfasalazine	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
34	cimetidine	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
35	haloperidol	0.5% MC	Gavage	Liver	3	10	30	3	10	30
36	fluphenazine	0.5% MC	Gavage	Liver	2	6	20	2	6	20
37	thioridazine	0.5% MC	Gavage	Liver	10	30	100	10	30	100
38	adapin	0.5% MC	Gavage	Liver	100	300	NoData	10	30	100
39	labetalol	0.5% MC	Gavage	Liver	45	150	450	45	150	450
40	methyltestosterone	0.5% MC	Gavage	Liver / Kidney	30	100	300	30	100	300
41	glibenclamide	corn oil	Gavage	Liver	100	300	1000	100	300	1000
42	griseofulvin	corn oil	Gavage	Liver	100	300	1000	100	300	1000
43	flutamide	corn oil	Gavage	Liver	15	50	150	15	50	150
44	perhexiline	0.5% MC	Gavage	Liver	15	50	150	15	50	150
45	azathioprine	0.5% MC	Gavage	Liver	3	10	30	3	10	30
46	ketoconazole	0.5% MC	Gavage	Liver / Kidney	10	30	100	10	30	100
47	tetracycline	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
48	lomustine	0.5% MC	Gavage	Liver / Kidney	0.6	2	6	0.6	2	6
49	ciprofloxacin	0.5% MC	Gavage	Liver / Kidney	100	300	1000	100	300	1000
50	pemoline	0.5% MC	Gavage	Liver	7.5	25	75	7.5	25	75
51	chlormezanone	corn oil	Gavage	Liver	50	150	500	50	150	500
52	metformin	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
53	tamoxifen	corn oil	Gavage	Liver	6	20	60	6	20	60
54	ethinylestradiol	corn oil	Gavage	Liver / Kidney	1	3	10	1	3	10
55	methyldopa	corn oil	Gavage	Liver	60	200	600	60	200	600
56	methimazole	0.5% MC	Gavage	Liver	10	30	100	10	30	100
57	monocrotaline	0.5% MC	Gavage	Liver / Kidney	3	10	30	3	10	30
58	vitamin A	corn oil	Gavage	Liver	10	30	100	10	30	100
59	tacrine	0.5% MC	Gavage	Liver	3	10	30	3	10	30
60	moxisylyte	0.5% MC	Gavage	Liver	50	150	500	50	150	500
61	iproniazid	0.5% MC	Gavage	Liver	6	20	60	6	20	60
62	chloramphenicol	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
63	nitrofurazone	0.5% MC	Gavage	Liver	30	100	300	10	30	100
64	imipramine	0.5% MC	Gavage	Liver / Kidney	10	30	100	10	30	100
65	amitriptyline	0.5% MC	Gavage	Liver	15	50	150	15	50	150
66	hydroxyzine	0.5% MC	Gavage	Liver	10	30	100	10	30	100
67	ibuprofen	0.5% MC	Gavage	Liver	60	200	400	20	60	200
68	naproxen	0.5% MC	Gavage	Liver	20	60	200	6	20	60
69	quinidine	0.5% MC	Gavage	Liver	20	60	200	20	60	200
70	furosemide	0.5% MC	Gavage	Liver	30	100	300	30	100	300
71	fenofibrate	0.5% MC	Gavage	Liver	10	100	1000	10	100	1000
72	chlorpropamide	0.5% MC	Gavage	Liver	30	100	300	30	100	300
73	nicotinic acid	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
74	erythromycin ethylsuccinate	0.5% MC	Gavage	Liver / Kidney	100	300	1000	100	300	1000
75	ethambutol	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
76	mefenamic acid	0.5% MC	Gavage	Liver	30	100	300	30	100	300
77	famotidine	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
78	ranitidine	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
79	chlorpheniramine	0.5% MC	Gavage	Liver	3	10	30	3	10	30
80	nifedipine	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
81	diltiazem	0.5% MC	Gavage	Liver	80	240	800	80	240	800
82	tannic acid	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
83	captopril	0.5% MC	Gavage	Liver / Kidney	100	300	1000	100	300	1000
84	enalapril	0.5% MC	Gavage	Liver / Kidney	60	200	600	60	200	600
85	theophylline	0.5% MC	Gavage	Liver	20	60	200	20	60	200
86	caffeine	0.5% MC	Gavage	Liver / Kidney	10	30	100	10	30	100
87	papaverine	0.5% MC	Gavage	Liver	40	120	400	40	120	400
88	penicillamine	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
89	sulindac	0.5% MC	Gavage	Liver	15	50	150	5	15	50
90	triamterene	0.5% MC	Gavage	Liver / Kidney	15	50	150	15	50	150
91	disopyramide	0.5% MC	Gavage	Liver	40	120	400	40	120	400
92	mexiletine	0.5% MC	Gavage	Liver	40	120	400	40	120	400
93	tiopronin	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
94	acetazolamide	0.5% MC	Gavage	Liver / Kidney	60	200	600	60	200	600
95	disulfiram	0.5% MC	Gavage	Liver	60	200	600	60	200	600
96	promethazine	0.5% MC	Gavage	Liver	20	60	200	20	60	200
97	colchicine	0.5% MC	Gavage	Liver	1.5	5	15	0.5	1.5	5
98	tolbutamide	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
99	sulpiride	0.5% MC	Gavage	Liver	300	1000	2000	100	300	1000
100	acarbose	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
101	simvastatin	0.5% MC	Gavage	Liver	40	120	400	40	120	400
102	ajmaline	0.5% MC	Gavage	Liver	30	100	300	30	100	300
103	dantrolene	0.5% MC	Gavage	Liver	25	75	250	25	75	250
104	triazolam	0.5% MC	Gavage	Liver	100	300	1000	100	300	1000
105	clomipramine	0.5% MC	Gavage	Liver	10	30	100	10	30	100
106	trimethadione	0.5% MC	Gavage	Liver	50	150	500	50	150	500
107	terbinafine	0.5% MC	Gavage	Liver	75	250	750	75	250	750
108	meloxicam	0.5% MC	Gavage	Liver	10	30	100	3	10	30
109	lornoxicam	0.5% MC	Gavage	Liver	1	3	10	0.3	1	3
110	chlormadinone	0.5% MC	Gavage	Liver	300	1000	2000	100	300	1000
111	danazol	0.5% MC	Gavage	Liver	300	1000	2000	100	300	1000
112	bendazac	0.5% MC	Gavage	Liver	100	300	1000	30	100	300
113	benziodarone	0.5% MC	Gavage	Liver	30	100	300	30	100	300
114	etoposide	0.5% MC	Gavage	Liver	10	100	1000	3	10	30
115	cisplatin	saline	intravenous injection	Liver / Kidney	0.3	1	3	0.1	0.3	1
116	carboplatin	saline	intravenous injection	Liver / Kidney	10	30	100	1	3	10
117	bromoethylamine	saline	intravenous injection	Liver / Kidney	6	20	60	2	6	20
118	ethionamide	0.5% MC	Gavage	Liver	100	300	1000	30	100	300
119	nimesulide	0.5% MC	Gavage	Liver	30	100	300	10	30	100
120	ethanol	distilled water	Gavage	Liver	400	1200	4000	400	1200	4000
121	phenacetin	0.5% MC	Gavage	Liver / Kidney	300	1000	2000	100	300	1000
122	bucetin	0.5% MC	Gavage	Liver / Kidney	300	1000	2000	100	300	1000
123	phenylanthranilic acid	0.5% MC	Gavage	Liver / Kidney	300	1000	2000	100	300	1000
124	cephalothin	saline	intravenous injection	Liver / Kidney	300	1000	2000	300	1000	2000
125	cyclosporine A	corn oil	Gavage	Liver / Kidney	30	100	300	10	30	100
126	puromycin aminonucleoside	saline	intravenous injection	Liver / Kidney	12	40	120	4	12	40
127	acetamidofluorene	0.5% MC	Gavage	Liver	100	300	1000	30	100	300
128	nitrosodiethylamine	0.5% MC	Gavage	Liver	10	30	100	3	10	30
129	ticlopidine	0.5% MC	Gavage	Liver	100	300	1000	30	100	300
130	gentamicin	saline	intravenous injection	Liver / Kidney	10	30	100	10	30	100
131	doxorubicin	saline	intravenous injection	Liver / Kidney	1	3	10	0.1	0.3	1
132	rosiglitazone maleate	0.5% MC	Gavage	Liver	20	100	500	2	20	100
133	rotenone	0.5% MC	Gavage	Liver	5	15	50	5	15	50
134	dexamethasone	0.5% MC	Gavage	Liver	0.5	5	50	NoData	NoData	NoData
135	2,4-dinitrophenol	0.5% MC	Gavage	Liver	6	20	60	6	20	60
136	methylene dianiline	corn oil	Gavage	Liver	30	100	300	10	30	100
137	butylated hydroxyanisole	corn oil	Gavage	Liver	300	1000	2000	300	1000	2000
138	amphotericin B	5% glucose sol., 1% DMSO, 0.001N HCl	intravenous injection	Liver / Kidney	0.6	2	4	0.1	0.3	1
139	fluoxetine hydrochloride	0.5% MC	Gavage	Liver	3	10	30	3	10	30
140	desmopressin acetate	saline	subcutaneous injection	Liver / Kidney	20	200	2000	2	20	200
141	2-nitrofluorene	corn oil	Gavage	Liver	100	300	1000	NoData	NoData	NoData
142	1% cholesterol + 0.25% sodium cholate	none	Diet	Liver	NoData	NoData	NoData	NoData	NoData	9999
143	N-nitrosomorpholine	0.5% MC	Gavage	Liver	100	300	600	NoData	NoData	NoData
144	N-methyl-N-nitrosourea	saline	intraperitoneal injection	Liver	10	30	100	NoData	NoData	NoData
145	aflatoxin B1	0.5% MC	Gavage	Liver	1	3	10	NoData	NoData	NoData
146	3-methylcholanthrene	corn oil	Gavage	Liver	10	30	100	NoData	NoData	NoData
147	acetamide	0.5% MC	Gavage	Liver	NoData	NoData	NoData	300	1000	2000
148	propranolol	0.5% MC	Gavage	Liver	15	50	150	15	50	150
149	alpidem	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
150	venlafaxine	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
151	buspirone	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
152	clozapine	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
153	nefazodone	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
154	interferon alpha, human	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
155	interleukin 1 beta, human	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
156	interleukin 6, human	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
157	transforming growth factor beta 1	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
158	hepatocyte growth factor, human	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
159	bortezomib	saline	intravenous injection	Liver	0.1	0.3	0.6	NoData	NoData	NoData
160	gefitinib	0.5% MC	Gavage	Liver	200	600	2000	NoData	NoData	NoData
161	imatinib, methanesulfonate salt	0.5% MC	Gavage	Liver	60	200	600	NoData	NoData	NoData
162	cycloheximide	saline	intravenous injection	Liver	1	3	10	NoData	NoData	NoData
163	tunicamycin	saline	intraperitoneal injection	Liver	30	100	300	NoData	NoData	NoData
164	phorone	corn oil	intraperitoneal injection	Liver	40	120	400	NoData	NoData	NoData
165	buthionine sulfoximine	saline	intraperitoneal injection	Liver	150	450	1500	NoData	NoData	NoData
166	diethyl maleate	corn oil	intraperitoneal injection	Liver	80	240	800	NoData	NoData	NoData
167	galactosamine	saline	intraperitoneal injection	Liver	100	300	1000	NoData	NoData	NoData
168	LPS	saline	intraperitoneal injection	Liver	10	300	3000	NoData	NoData	NoData
169	TNFα	0.5% BSA saline	intraperitoneal injection	Liver	1	3	10	NoData	NoData	NoData
170	phalloidin	saline	intraperitoneal injection	Liver	NoData	NoData	0.5	NoData	NoData	0.5
公開対象　in vitroデータ in vivoデータへ
	化合物名（英）	溶媒	Cell	Rat試験投与量 （μM）			Human試験投与量 （μM）			備考
				Low	Middle	High	Low	Middle	High
1	acetaminophen	medium	Hepatocyte	1000	3000	10000	200	1000	5000
2	isoniazid	medium	Hepatocyte	400	2000	10000	400	2000	10000
3	carbon tetrachloride	DMSO	Hepatocyte	1000	3000	10000	300	1500	7500
4	phenobarbital	medium	Hepatocyte	1000	3000	10000	400	2000	10000
5	valproic acid	medium	Hepatocyte	400	2000	10000	200	1000	5000
6	clofibrate	DMSO	Hepatocyte	12	60	300	12	60	300
7	rifampicin	DMSO	Hepatocyte	2.8	14	70	2.8	14	70
8	naphthyl isothiocyanate	DMSO	Hepatocyte	8	40	200	8	40	200
9	allyl alcohol	medium	Hepatocyte	0.8	4	20	2.8	14	70
10	phenylbutazone	DMSO	Hepatocyte	16	80	400	16	80	400
11	omeprazole	DMSO	Hepatocyte	4.8	24	120	24	120	600
12	ethionine	medium	Hepatocyte	400	2000	10000	400	2000	10000
13	aspirin	DMSO	Hepatocyte	120	600	3000	120	600	3000
14	indomethacin	DMSO	Hepatocyte	12	60	300	8	40	200
15	chlorpromazine	DMSO	Hepatocyte	0.8	4	20	0.8	4	20
16	thioacetamide	medium	Hepatocyte	400	2000	10000	400	2000	10000
17	carbamazepine	DMSO	Hepatocyte	12	60	300	12	60	300
18	diclofenac	DMSO	Hepatocyte	16	80	400	16	80	400
19	nitrofurantoin	DMSO	Hepatocyte	5	25	125	5	25	125
20	benzbromarone	DMSO	Hepatocyte	0.6	3	15	4	20	100
21	hexachlorobenzene	DMSO	Hepatocyte	0.6	3	15	1.2	6	30
22	diazepam	DMSO	Hepatocyte	5	25	125	10	50	250
23	cyclophosphamide	medium	Hepatocyte	8	40	200	80	400	2000
24	methapyrilene	medium	Hepatocyte	0.6	3	15	24	120	600
25	phenytoin	DMSO	Hepatocyte	2.4	12	60	2.4	12	60
26	coumarin	DMSO	Hepatocyte	12	60	300	12	60	300
27	allopurinol	DMSO	Hepatocyte	5.6	28	140	5.6	28	140
28	propylthiouracil	medium	Hepatocyte	160	800	4000	160	800	4000
29	WY-14643	DMSO	Hepatocyte	8	40	200	6	30	150
30	gemfibrozil	DMSO	Hepatocyte	4	20	100	4	20	100
31	bromobenzene	DMSO	Hepatocyte	8	40	200	8	40	200
32	amiodarone	DMSO	Hepatocyte	0.28	1.4	7	0.28	1.4	7
33	sulfasalazine	DMSO	Hepatocyte	4	20	100	6	30	150
34	cimetidine	DMSO	Hepatocyte	12	60	300	12	60	300
35	haloperidol	DMSO	Hepatocyte	2	10	50	0.8	4	20
36	fluphenazine	medium	Hepatocyte	1.2	6	30	0.8	4	20
37	thioridazine	DMSO	Hepatocyte	0.4	2	10	0.6	3	15
38	adapin	DMSO	Hepatocyte	3	15	75	3	15	75
39	labetalol	medium	Hepatocyte	5.6	28	140	5.6	28	140
40	methyltestosterone	DMSO	Hepatocyte	1.6	8	40	0.8	4	20
41	glibenclamide	DMSO	Hepatocyte	2.4	12	60	0.8	4	20
42	griseofulvin	DMSO	Hepatocyte	1.2	6	30	0.8	4	20
43	flutamide	DMSO	Hepatocyte	3	15	75	2	10	50
44	perhexiline	DMSO	Hepatocyte	0.4	2	10	0.6	3	15
45	azathioprine	DMSO	Hepatocyte	0.14	0.72	3.6	2.9	14.6	72.8
46	ketoconazole	DMSO	Hepatocyte	0.6	3	15	0.6	3	15
47	tetracycline	DMSO	Hepatocyte	1	5	25	1	5	25
48	lomustine	DMSO	Hepatocyte	4.8	24	120	4.8	24	120
49	ciprofloxacin	DMSO	Hepatocyte	1	5	25	NoData	5	25
50	pemoline	DMSO	Hepatocyte	3	15	75	NoData	15	75
51	chlormezanone	DMSO	Hepatocyte	10	50	250	NoData	50	250
52	metformin	medium	Hepatocyte	40	200	1000	NoData	200	1000
53	tamoxifen	DMSO	Hepatocyte	0.12	0.6	3	NoData	5	25
54	ethinylestradiol	DMSO	Hepatocyte	0.6	3	15	NoData	3	15
55	methyldopa	medium	Hepatocyte	2	10	50	NoData	10	50
56	methimazole	medium	Hepatocyte	400	2000	10000	NoData	2000	10000
57	monocrotaline	DMSO	Hepatocyte	3.6	18	90	NoData	18	90
58	vitamin A	DMSO	Hepatocyte	0.3	1.5	7.5	NoData	1.5	7.5
59	tacrine	medium	Hepatocyte	8	40	200	NoData	16	80
60	moxisylyte	medium	Hepatocyte	24	120	600	NoData	80	400
61	iproniazid	medium	Hepatocyte	80	400	2000	NoData	240	1200
62	chloramphenicol	DMSO	Hepatocyte	18	90	450	NoData	90	450
63	nitrofurazone	DMSO	Hepatocyte	12	60	300	NoData	10	50
64	imipramine	DMSO	Hepatocyte	4	20	100	NoData	3	15
65	amitriptyline	DMSO	Hepatocyte	2.4	12	60	NoData	3	15
66	hydroxyzine	medium	Hepatocyte	6	30	150	NoData	8	40
67	ibuprofen	medium	Hepatocyte	40	200	1000	NoData	30	150
68	naproxen	medium	Hepatocyte	80	400	2000	NoData	120	600
69	quinidine	medium	Hepatocyte	8	40	200	NoData	10	50
70	furosemide	medium	Hepatocyte	100	500	2500	NoData	500	2500
71	fenofibrate	DMSO	Hepatocyte	1.2	6	30	NoData	6	30
72	chlorpropamide	DMSO	Hepatocyte	30	150	750	NoData	150	750
73	nicotinic acid	medium	Hepatocyte	400	2000	10000	NoData	2000	10000
74	erythromycin ethylsuccinate	DMSO	Hepatocyte	3	15	75	NoData	1	5
75	ethambutol	medium	Hepatocyte	160	800	4000	NoData	800	4000
76	mefenamic acid	DMSO	Hepatocyte	6	30	150	NoData	30	150
77	famotidine	DMSO	Hepatocyte	28	140	700	NoData	140	700
78	ranitidine	medium	Hepatocyte	160	800	4000	NoData	800	4000
79	chlorpheniramine	medium	Hepatocyte	8	40	200	NoData	18	90
80	nifedipine	DMSO	Hepatocyte	10	50	250	NoData	30	150
81	diltiazem	DMSO	Hepatocyte	10	50	250	NoData	30	150
82	tannic acid	DMSO	Hepatocyte	0.4	2	10	NoData	1	5
83	captopril	medium	Hepatocyte	400	2000	10000	NoData	1600	8000
84	enalapril	medium	Hepatocyte	80	400	2000	NoData	400	2000
85	theophylline	medium	Hepatocyte	400	2000	10000	NoData	2000	10000
86	caffeine	medium	Hepatocyte	400	2000	10000	NoData	1500	7500
87	papaverine	medium	Hepatocyte	4	20	100	NoData	12	60
88	penicillamine	medium	Hepatocyte	400	2000	10000	NoData	2000	10000
89	sulindac	medium	Hepatocyte	80	400	2000	NoData	600	3000
90	triamterene	DMSO	Hepatocyte	1.2	6	30	NoData	NoData	NoData
91	disopyramide	medium	Hepatocyte	100	500	2500	NoData	700	3500
92	mexiletine	medium	Hepatocyte	0.6	3	15	NoData	60	300
93	tiopronin	medium	Hepatocyte	1	5	25	NoData	400	2000
94	acetazolamide	DMSO	Hepatocyte	24	120	600	NoData	120	600
95	disulfiram	DMSO	Hepatocyte	2.4	12	60	NoData	12	60
96	promethazine	DMSO	Hepatocyte	3.2	16	80	NoData	7	35
97	colchicine	medium	Hepatocyte	200	1000	5000	NoData	800	4000
98	tolbutamide	medium	Hepatocyte	80	400	2000	NoData	400	2000
99	sulpiride	medium	Hepatocyte	200	1000	5000	NoData	1000	5000
100	acarbose	medium	Hepatocyte	400	2000	10000	NoData	2000	10000
101	simvastatin	DMSO	Hepatocyte	2.4	12	60	NoData	6	30
102	ajmaline	DMSO	Hepatocyte	12	60	300	NoData	60	300
103	dantrolene	DMSO	Hepatocyte	0.4	2	10	NoData	2	10
104	triazolam	DMSO, 0.5% DMSO	Hepatocyte	0.4	2	10	0.4	2	10
105	clomipramine	DMSO	Hepatocyte	1.6	8	40	NoData	2	10
106	trimethadione	medium	Hepatocyte	400	2000	10000	400	2000	10000
107	terbinafine	DMSO	Hepatocyte	0.6	3	15	NoData	3	15
108	meloxicam	DMSO	Hepatocyte	2	10	50	NoData	10	50
109	lornoxicam	DMSO	Hepatocyte	0.6	3	15	NoData	3	15
110	chlormadinone	DMSO	Hepatocyte	1.6	8	40	NoData	8	40
111	danazol	DMSO	Hepatocyte	1.4	7	35	NoData	7	35
112	bendazac	medium	Hepatocyte	8	40	200	8	40	200
113	benziodarone	DMSO	Hepatocyte	1	5	25	NoData	8	40
114	etoposide	DMSO	Hepatocyte	14	70	350	NoData	66	330
115	cisplatin	DMSO	Hepatocyte	8	40	200	NoData	NoData	NoData
116	carboplatin	medium	Hepatocyte	120	600	3000	NoData	NoData	NoData
117	bromoethylamine	medium	Hepatocyte	20	100	500	20	100	500
118	ethionamide	DMSO	Hepatocyte	24	120	600	NoData	120	600
119	nimesulide	DMSO	Hepatocyte	3	15	75	NoData	66	330
120	ethanol	medium	Hepatocyte	400	2000	10000	NoData	2000	10000
121	phenacetin	DMSO	Hepatocyte	24	120	600	NoData	120	600
122	bucetin	DMSO	Hepatocyte	12	60	300	NoData	60	300
123	phenylanthranilic acid	DMSO	Hepatocyte	8	40	200	NoData	40	200
124	cephalothin	medium	Hepatocyte	120	600	3000	NoData	NoData	NoData
125	cyclosporine A	DMSO, 0.5% DMSO	Hepatocyte	0.24	1.2	6	0.24	1.2	6
126	puromycin aminonucleoside	medium	Hepatocyte	100	500	2500	NoData	NoData	NoData
127	acetamidofluorene	DMSO	Hepatocyte	2	10	50	NoData	10	50
128	nitrosodiethylamine	medium	Hepatocyte	400	2000	10000	NoData	2000	10000
129	ticlopidine	DMSO	Hepatocyte	2.4	12	60	NoData	4	20
130	gentamicin	medium	Hepatocyte	1.2	6	30	NoData	NoData	NoData	投与量単位はmg/mL
131	doxorubicin	DMSO, 0.5% DMSO	Hepatocyte	0.08	0.4	2	0.4	2	10
132	rosiglitazone maleate	0.5% DMSO	Hepatocyte	NoData	NoData	NoData	12	60	300
133	rotenone	medium	Hepatocyte	NoData	NoData	NoData	0.08	0.4	2
134	dexamethasone	0.5% DMSO	Hepatocyte	NoData	NoData	NoData	12	60	300
135	2,4-dinitrophenol	medium	Hepatocyte	NoData	NoData	NoData	4	20	100
136	methylene dianiline	medium	Hepatocyte	NoData	NoData	NoData	24	120	600
137	butylated hydroxyanisole	medium	Hepatocyte	NoData	NoData	NoData	8	40	200
138	amphotericin B	DMSO	Hepatocyte	NoData	NoData	NoData	0.08	0.4	2
139	fluoxetine hydrochloride	DMSO	Hepatocyte	NoData	NoData	NoData	4	8	20
140	desmopressin acetate	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
141	2-nitrofluorene	0.5% DMSO	Hepatocyte	NoData	NoData	NoData	4	20	100
142	1% cholesterol + 0.25% sodium cholate	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
143	N-nitrosomorpholine	medium	Hepatocyte	NoData	NoData	NoData	400	2000	10000
144	N-methyl-N-nitrosourea	medium	Hepatocyte	NoData	NoData	NoData	1200	6000	10000
145	aflatoxin B1	DMSO	Hepatocyte	NoData	NoData	NoData	0.24	1.2	6
146	3-methylcholanthrene	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
147	acetamide	medium	Hepatocyte	NoData	NoData	NoData	400	2000	10000
148	propranolol	medium	Hepatocyte	NoData	NoData	NoData	6	30	100
149	alpidem	DMSO	Hepatocyte	10	NoData	NoData	NoData	3	10
150	venlafaxine	medium	Hepatocyte	1200	NoData	NoData	NoData	240	1200
151	buspirone	medium	Hepatocyte	70	NoData	NoData	NoData	6	30
152	clozapine	DMSO	Hepatocyte	120	NoData	NoData	NoData	10	50
153	nefazodone	DMSO	Hepatocyte	70	NoData	NoData	NoData	6	30
154	interferon alpha, human	medium	Hepatocyte	NoData	NoData	NoData	2	10	50
155	interleukin 1 beta, human	medium	Hepatocyte	NoData	NoData	NoData	2	10	50
156	interleukin 6, human	medium	Hepatocyte	NoData	NoData	NoData	2	10	50
157	transforming growth factor beta 1	medium	Hepatocyte	NoData	NoData	NoData	2	10	50
158	hepatocyte growth factor, human	medium	Hepatocyte	NoData	NoData	NoData	2	10	50
159	bortezomib	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
160	gefitinib	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
161	imatinib, methanesulfonate salt	NoData	NoData	NoData	NoData	NoData	NoData	NoData	NoData
162	cycloheximide	medium	Hepatocyte	4	20	100	4	20	100
163	tunicamycin	medium	Hepatocyte	2	10	50	0.4	2	10
164	phorone	medium	Hepatocyte	20	100	500	200	1000	5000
165	buthionine sulfoximine	medium	Hepatocyte	400	2000	10000	400	2000	10000
166	diethyl maleate	medium	Hepatocyte	60	300	1500	60	300	1500
167	galactosamine	medium	Hepatocyte	400	2000	10000	400	2000	10000
168	LPS	medium	Hepatocyte	0.16	0.8	4	12	60	300
169	TNFα	medium	Hepatocyte	2	10	50	2	10	50
170	phalloidin	medium, 0.5% DMSO	Hepatocyte	4	20	100	16	80	400
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